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The Min Lu Research Group
Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
State Key Laboratory of Omics and Disease (formerly State Key Laboratory of Medical Genomics)
English
English
中文 (中国)
English
English
中文 (中国)
The Min Lu Research Group
Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
State Key Laboratory of Omics and Disease (formerly State Key Laboratory of Medical Genomics)
English
English
中文 (中国)
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Database(rescue p53)
癌症与p53科普-en
Contact Us
Home
Research
Achievements
Group News
Scholarly Developments
Life Moments
Research Group Members
Database(rescue p53)
癌症与p53科普-en
Contact Us
The research on p53 targeted drugs (i.e. drugs that can restore the anti-cancer function of p53 mutants) is highly challenging for two reasons
mougen
May 30, 2022
5:21 pm
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Although at least 45 teams worldwide are researching drugs to treat p53 mutations, currently only arsenic agents can target p53 mutants and restore their anti-cancer function
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Although these over 1000 p53 mutations all cause p53 to lose its anti-tumor function, there are multiple pathways through which they cause p53 to lose its function. Therefore, different p53 mutants cannot be confused
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