What are the top ten factors that cause cancer?
Age cannot be prevented, but smoking, drinking, and obesity can be prevented
The probability of cancer occurrence and death among residents increases significantly with age
Taking you as an example, after reaching the age of 40, annual check ups become even more important; Most early-stage cancers can be cured, while most late stage cancers cannot be cured
Top 10 Facts About Cancer
Dai Min, Director of the International Exchange Department of the National Cancer Center, revealed ten facts about cancer: Fact 1: There are over 100 types of cancer, and any part of the body can be affected. Fact 2: China’s cancer incidence rate is basically the same as the global average, but China’s cancer mortality is […]
Mutation of tumor suppressor genes and oncogenes is a major factor in the occurrence and death of cancer
The 100 genes with the highest mutation frequency in cancer
About 80% of them belong to tumor suppressor genes or oncogenes, and the tumor suppressor gene p53 is the gene with the highest mutation frequency in cancer
The tumor suppressor gene p53 undergoes mutations in half of cancer patients, with varying mutation frequencies across different types of cancer
More than 1000 different p53 mutants have been detected in cancer so far
The 25 most common p53 mutants
Loss of anti-tumor function after p53 mutation is one of the main factors leading to cancer occurrence and death
Compared to patients without p53 mutations, patients with p53 mutations often have a lower probability of surviving for more than 5 years
Although these over 1000 p53 mutations all cause p53 to lose its anti-tumor function, there are multiple pathways through which they cause p53 to lose its function. Therefore, different p53 mutants cannot be confused