The Min Lu Research Group

Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
State Key Laboratory of Omics and Disease (formerly State Key Laboratory of Medical Genomics)

The Min Lu Research Group

Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
State Key Laboratory of Omics and Disease (formerly State Key Laboratory of Medical Genomics)

Xueqin Chen

Post-Doctoral

Research Direction

Small molecule anti-tumor drugs

Academic Experience

2025 present: Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine (postdoctoral)

Lead The Project

2023 National Natural Science Foundation of China Young Student Basic Research Project (PhD Program), 823B2004

2017 Guangzhou University Innovation and Entrepreneurship Training Project (Key), 2017034106

Honors And Awards

2024 Shanghai Jiao Tong University First Class Scholarship

First Prize in the 2018 National College Student Life Science Innovation and Entrepreneurship Competition

2018 Jinan University Innovation Competition Finals Special Prize and Best Project Award

Patent

1. Lu Min, Chen Xueqin, Zhao Yinping, Wu Jiaqi; Application of RIG-I inducer in the preparation of drugs for treating DNA demethylation resistant acute myeloid leukemia, 6

2. Lu Min, Dong Jiajia, Wu Jiaqi, Li Qianqian, Chen Xueqin, Jiang Ying, Zheng Derun, Guo Taijie, Xiao Shujun, Ma Tiancheng; Multivalent molecular gel compounds and their preparation and application, 2024, 11363354.2

3. Dong Jiajia, Lu Min, Li Qianqian, Wu Jiaqi, Guo Taijie, Chen Xueqin, Jiang Ying, Zheng Derun, Ma Tiancheng, Song Huaxin, Xia Shuang, Wang Xiaolei; A modular molecular gel compound library and its construction method and application, 7
Publish A Paper
  1. Chen X#, Liu J#, Li Y#, Zeng Y, Wang F, Cheng Z, Duan H, Pan G, Yang S, Chen Y, Li Q, Shen X, Li Y, Qin Z, Chen J, Huang Y, Wang X, Lu Y, Shu M, Zhang Y, Wang G, Li K, Lin X*, Xing F*, Zhang H*. IDH1 mutation impairs antiviral response and potentiates oncolytic virotherapy in glioma. Nat Commun. 2023 Oct 25;14(1):6781(第一作者，IF = 16.6)
  2. Chen X#, WuJ#, Li Y#, …, Lu M*. RIG-I-inducing small molecules potently inhibit HMA-resistant AML through igniting the overloaded dsRNA arsenal. Adv Sci. In revision (第一作者，IF = 14.3)
  3. Xiao S#, Shi F#, Song H#, Cui J#, Zheng D, Zhang H, Tan K, Wu J, Chen X, Wu J, Tang Y, Dai Y*, Lu M*. Characterization of the generic mutant p53-rescue compounds in a broad range of assays. Cancer Cell. 2024 Mar 11;42(3):325-327(共同作者，IF = 50.3)
  4. Li J#, Zhang S#, Wang B#, Dai Y#, Wu J#, Liu D, Liang Y, Xiao S, Wang Z, Wu J, Zheng D, Chen X, Shi F, Tan K, Ding X*, Song H*, Zhang S*, Lu M*. Pharmacological rescue of mutant p53 triggers spontaneous tumor regression via immune responses. Cell Rep Med. 2025 Feb 12:101976(共同作者，IF = 11.7)
  5. Huang Y#, Wang F#, Lin X#, Li Q, Lu Y, Zhang J, Shen X, Tan J, Qin Z, Chen J, Chen X, Pan G, Wang X, Zeng Y, Yang S, Liu J, Xing F*, Li K*, Zhang H*. Nuclear VCP drives colorectal cancer progression by promoting fatty acid oxidation. PNAS. 2023 Oct 10;120(41):e2221653120(共同作者，IF = 11.1)
  6. Wang F#, Qi Q#, Qin B#, Wang Y, Huang Y, Li Q, Shen X, Wang X, Yang S, Pan G, Chen J, Qin Z, Chen X, Yang Y, Zeng Y, Liu J, Li Y, Li Y, Cheng Z, Lin X, Xing F, Zhang Y, Wang G, Li K*, Jiang Z*, Zhang H*. Targeting VCP potentiates immune checkpoint therapy for colorectal cancer. Cell Rep. 2023 Nov 28;42(11):113318(共同作者，IF = 8.8)
  7. Qin Z#, Huang Y#, Li Z#, Pan G, Zheng L, Xiao X, Wang F, Chen J, Chen X, Lin X, Li K, Yan G, Zhang H*, Xing F*. Glioblastoma Vascular Plasticity Limits Effector T-cell Infiltration and Is Blocked by cAMP Activation. Cancer Immunol Res. 2023 Oct 4;11(10):1351-1366(共同作者，IF = 10.1)
  8. Li J#, Xiao S#, Shi F#, Song H, Wu J, Zheng D, Chen X, Tan K, Lu M*. Arsenic trioxide extends survival of Li-Fraumeni syndrome mimicking mouse. Cell Death Dis. 2023 Nov 29;14(11):783(共同作者，IF = 9.0)

The Min Lu Research Group

Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
State Key Laboratory of Omics and Disease (formerly State Key Laboratory of Medical Genomics)
  • 021-64370045 
  • min.lu@@shsmu.edu.cn
  • No. 197, Ruijin Er Road, Huangpu District, Shanghai, China

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